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Causes and Treatment for BPD

Causes

  • Impaired brain chemistry (treated with medications). The neurotransmitters dopamine, serotonin, acetylcholine, and norepinephrine may be involved.

  • Early environmental influences (anything from long-term isolation for an early infectious disease to severe physical or sexual abuse).

  • Triggers that bring on symptoms (such as divorce or adolescent traumas).

Treatment

When a person with BPD allows themselves to be treated (denial is often part of the disorder), treatment generally consists of:

  • Medications, which are often successfully used to reduce depression, dampen emotional ups and downs, and put the brakes on excessive impulsivity. Antidepressants can help with depression, while mood stabilizers such as Depakote, Tegretol, or Lithium can help with mood swings. Selective Serotonin Re-uptake Inhibitors (SSRIs) such as Prozac, Zoloft, and Paxil may help control impulsivity, as may Effexor, a related antidepressant. Tegretol may be helpful for controlling excessive anger and irritability.

  • Therapy, especially cognitive-behavioral therapy. The major problems are finding a qualified therapist and getting the BP into therapy. Researcher Marsha Linehan’s cognitive-behavioral method of treatment, called Dialectical Behavior Therapy (DBT), has been shown in empirical research to help BPD patients experience less anger, less self-mutilation, and fewer inpatient psychiatric stays than patients who received other forms of treatment. For more on DBT. see http://faculty.washington.edu/linehan/ 

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